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Luan et al., 2019)

Nonreceptor tyrosine kinases in prostate cancer

FDA Approval Semaglutide (Wegovy) is FDA-approved for: Adults with a BMI 30 (obesity) or BMI 27 (overweight) with at least one weight-related condition like hypertension or type 2 diabetes

Under diabetic conditions, glomerular podocytes secrete this hyposialylated ANGPTL4, which plays a significant role in disrupting lipid metabolism, promoting inflammation, and driving fibrosis in both podocytes and adjacent tubules